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DRUG SAFETY ALERT

IMPORTANT DRUG SAFETY ALERT
    MICONAZOLE

(DAKTARIN, DAKTACORT)

A drug safety alert has been issued for Miconazole (Daktarin ,Daktacort) including      he topical gel formulation used for fungal infection control. It has been found that Miconazole can enhance the anti-coagulant effect of Warfarin. If Miconazole and Warfarin are used concurrently, the effect should be carefully monitored and if necessary the Warfarin dose reduced.

Patients are advised to tell their doctor or pharmacist if they are receiving warfarin before using products that contain miconazole (including those available without prescription), and to seek medical advice if they notice signs of over-anticoagulation during treatment, such as sudden unexplained bruising, nosebleeds or blood in the urine

For further information visit

www.gov.uk/drug-safety-update/topical-miconazole-including-oral-gel-reminder-of-potential-for-serious-interactions-with-warfarin

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